Nature, Published online: 03 September 2026; doi:10.1038/s41586-026-11091-5

Ketone homologation via palladium-catalysed decarboxylative rearrangement

Nature, Published online: 03 September 2026; doi:10.1038/d41586-026-02765-1

Results from a small trial suggest a modified virus can instruct the immune system to wipe out disease-causing cells.

Nature, Published online: 03 September 2026; doi:10.1038/d41586-026-02744-6

Study shows that psilocybin acts on nerves to prevent the painful condition called peripheral neuropathy.

Nature, Published online: 03 September 2026; doi:10.1038/d41586-026-02517-1

India, Peru and Vietnam are rolling out policies that limit opportunities for scientists who fall foul of research-integrity guidelines.

Nature, Published online: 03 September 2026; doi:10.1038/d41586-026-02781-1

Mice on GLP-1s also performed better on cognitive tasks than those on a calorie restricted diet . Plus, satellite images showed early warning signs of glacier collapse near the Nepal–Tibet border and the impact of people saying fewer words aloud.

Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02761-5

Researchers identify more than 1,200 personality-linked genetic variants, with effects largely independent of family background.

Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02745-5

Results bolster hopes that the drug daraxonrasib could prove effective against a variety of tumours.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-11104-3

Author Correction: Endocannabinoids facilitate reward engagement through retrograde gain control

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-11080-8

Author Correction: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-11027-z

Retraction Note: Warming accelerates global drought severity

Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02762-4

Researchers are hunting for ways to enhance DNA repair with the hopes that this will keep people healthier for longer.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10982-x

Inflammation induces interchromosomal DNA interactions that bring parent genes into close proximity, facilitating the formation of chimeric mRNAs that encode physiologically relevant, functional proteins.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10987-6

Integrative 3D epigenomic profiling of four glial cell types from the mid-gestation human cortex reveals cell-type-specific regulatory elements and chromatin interactions that illuminate the roles of non-coding variants in neuropsychiatric disease and human-specific cortical evolution.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10690-6

Connectomics, electrophysiology and modelling of electric fish neural circuits shows how distributed synaptic plasticity across multiple network layers cooperates to enable fast, accurate and noise-robust sensory learning.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10898-6

Artificial intelligence in physics experimental design is explored on the basis of searching for optima over a vast space of hardware configurations and proposing entirely new experimental layouts, rather than tuning a handful of parameters.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10952-3

Synthetic virus-like protein architectures designed by artificial intelligence show superior ability to deliver RNA into cells, compared with their naturally occurring counterparts, by overcoming the evolutionary constraints limiting viral evolution.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10940-7

Semaglutide treatment for 3 months in female mice improved physiological function, attenuated hallmarks of ageing and modulated nutrient sensors and conserved genetic regulators of ageing.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10992-9

The genetic architecture of personality is robustly generalizable, minimally confounded and widely relevant to human experience.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10818-8

Polarization and quantum entanglement measurements of baryon semileptonic decay greatly enhance single-event sensitivity, and combined with lattice quantum chromodynamics calculations enable determination of the |Vus| element of the Cabibbo–Kobayashi–Maskawa matrix, providing an independent test of the standard model.

Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10983-w

The atmospheric methane plateau can be explained by tropical hydroxyl radical enhancement primarily driven by a global rise and spatial redistribution of nitrogen oxides emissions towards developing regions and the oceans.