Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11110-5

Inflection points and transitions in Alzheimer’s disease

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11123-0

Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02833-6

A strong magnetic field can disrupt a star’s ability to produce the fountains of matter called coronal mass ejections.

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02927-1

Extensive cellular integration might provide platform for in vivo testing of new therapies — plus, the AI tool that turns papers into ‘virtual corresponding authors’.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11013-5

An approach to improve efficiency and establish a background expectation for ligand potency optimization is described.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11032-2

Xenocortication with human neurons enables circuit- and behaviour-level analysis of neurodevelopment in mice.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11020-6

The mitochondrial–peroxisomal fission adaptor MFF is identified as a selective pro-ferroptotic mediator, and the newly developed MFF–SPARK sensor enables high-content screening of ferroptosis-sensitizing compounds and the discovery of upstream regulators of MFF.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11044-y

Paper2Agent converts research papers into interactive artificial intelligence agents by turning manuscripts, code and data into model context protocol-based tool-invoking systems that reproduce original results, answer new scientific queries and collaborate to generate novel insights.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11042-0

Electroluminescent photoresists synthesized via atom transfer radical polymerization can be directly patterned by ultraviolet and electron-beam lithography, and used to fabricate monolithic, multicolour organic-light-emitting-diode micro-pixel arrays.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11011-7

Absorption spectroscopy of thorium-229 nuclear excited states in a thorium-doped calcium fluoride crystal demonstrates a path towards a much more efficient way to build a highly stable and robust solid-state optical nuclear clock.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11030-4

How respiratory syncytial virus mutations affect antibody neutralization is defined, and a biophysical model of the mechanism is provided, to show how Fab potency and epitope specificity combine to determine the effects of viral mutations on antibody neutralization.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11035-z

A rapid autopsy programme provides valuable resources to enable detailed molecular and genetic analyses of the temporal evolution of aggressive histological subtypes and therapy resistance in metastatic bladder cancer.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11026-0

Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, reward-prediction errors and disregard of reward-predictive cues, supporting flexible learning behaviour.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-10985-8

Observations from the JWST reveal an unexpectedly abundant population of little red dots and overmassive black holes in the early Universe, which are confirmed by their formation in fully cosmological radiation-hydrodynamic simulations.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11014-4

MEIS2, encoding a transcription factor linked to intellectual disability and autism spectrum disorder, is a key hub of a retinoic-acid-associated gene regulatory network.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11019-z

Researchers demonstrate successful road transport of trapped antiprotons, establishing a practical method for moving antimatter to quieter laboratories and substantially improving future tests of matter–antimatter symmetry.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11021-5

A mechanistic basis for how the hormone salicylic acid promotes transcriptional activation during plant immune responses is described.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11045-x

xvr makes pan-anatomical 2D/3D rigid registration accessible to broad clinical and research communities.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11000-w

A framework consisting of advanced epitaxy and layer lift-off techniques uses heterogeneous photonic integration of single-crystalline nanomembranes to infuse desired functionalities into silicon and silicon nitride photonics, demonstrating ultraefficient electro-optical and magneto-optical modulation.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-10948-z

Using mass photometry combined with a single-molecule trapping method allows real-time monitoring of the assembly of individual virus-like particles with molecular resolution, enabling observation and quantification of their self-assembly pathways and dynamics.